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Mapping of lateral geniculate nucleus activation during visual stimulation in human brain using fMRI

✍ Scribed by Wei Chen; Toshinori Kato; Xiao-Hong Zhu; John Strupp; Seiji Ogawa; Kǎmil Uǧurbil

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
967 KB
Volume
39
Category
Article
ISSN
0740-3194

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✦ Synopsis

Functional magnetic resonance imaging has been successfully used to map the activation in the lateral geniculate nucleus (LGN) in both hemispheres as well as the primary visual cortex (V1) during a checkerboard visual stimulation. The average blood oxygenation level dependent (BOLD) change in LGN was less than that in V1. However, the BOLD temporal responses were similar between LGN and V1. The activation in the pulvinar nucleus during visual perception was also detected, and its activated location could be separated from LGN in 3D images. The LGN activation between intersubject and intrasubject multiple trials was compared. The results demonstrate that fMRI can reliably and robustly detect small subcortical nucleus activation in the human brain.

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