Mapping of bovine prolactin and rhodopsin genes in hybrid somatic cells
β Scribed by E. M. HALLERMAN; J. L. THEILMANN; J. S. BECKMANN; M. SOLLER; J. E. WOMACK
- Book ID
- 114705507
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 462 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0268-9146
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Uridine monophosphate synthase (UMPS) catalyzes the final two steps of de novo pyrimidine synthesis, converting orotic acid to uridine 5' monophosphate. In Holstein and Red Holstein cattle, deficiency of UMPS (DUMPS) is inherited as a monogenic autosomal recessive trait. Heterozygous animals are phe
## Summary A bovine/hamster hybrid cell panel consisting of 30 independent hybrids was developed to locate genes. Polymerase chain reaction analysis of 279 microsatellites on the cattle linkage map in this panel revealed the presence of all chromosomes in either entire or fragmented form. Among pri