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Mapping of antigenic determinants of hepatitis C virus proteins using phage display

✍ Scribed by E. A. Rechkina; G. F. Denisova; O. V. Masalova; L. F. Lideman; D. A. Denisov; E. I. Lesnova; R. I. Ataullakhanov; S. V. Gurianova; A. A. Kushch

Book ID
110174331
Publisher
SP MAIK Nauka/Interperiodica
Year
2006
Tongue
English
Weight
326 KB
Volume
40
Category
Article
ISSN
0026-8933

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✍ Pereboeva, L. A.; Pereboev, A. V.; Morris, G. E. πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 489 KB πŸ‘ 1 views

A novel approach to screening phage-displayed peptide libraries has been used to identify hepatitis C virus (HCV) core, NS4 and NS5 sequences, which are antigenic in humans. Two random peptide libraries were used for screening using a mixture of HCV-positive sera or individual antibodies to core, NS