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Mapping a tumor suppressor gene to chromosome 2p13 in metanephric adenoma by microsatellite allelotyping

✍ Scribed by Tamas Pesti; Farkas Sükösd; Edward C Jones; Gyula Kovacs


Book ID
117818360
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
291 KB
Volume
32
Category
Article
ISSN
1532-8392

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Molecular mapping of chromosome 2 deleti
✍ Andrew Silver; John Moody; Rosemary Dunford; Debbie Clark; Sue Ganz; Robert Bulm 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB 👁 3 views

Radiation-induced acute myeloid leukemias (AMLs) in the mouse are characterized by chromosome 2 deletions. Previous studies showed that a minimal deleted region (mdr) of ϳ6.5 cM is lost from one homologue in chromosome 2-deleted AMLs. An AML tumor suppressor gene is proposed to map within this mdr.