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Mapping a Heparin Binding Site on ErbB-3 Epidermal Growth Factor Receptor

✍ Scribed by Rivka Adar; Avner Yayon

Book ID
115587812
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
195 KB
Volume
283
Category
Article
ISSN
0006-291X

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## Abstract ## BACKGROUND. Cleavage of membrane‐anchored heparin‐binding epidermal growth factor‐like growth factor (proHB‐EGF) yields a soluble HB‐EGF isoform (sHB‐EGF), which is an activating epidermal growth factor receptor (EGFR) ligand and a C‐terminal fragment HB‐EGF‐C acting directly in the