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Epiregulin binds to epidermal growth factor receptor and ErbB-4 and induces tryosine phosphorylation of epidermal growth factor receptor, ErbB-2, ErbB-3 and ErbB-4

✍ Scribed by Komurasaki, Toshi; Toyoda, Hitoshi; Uchida, Daisuke; Morimoto, Shigeo


Book ID
110061032
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
232 KB
Volume
15
Category
Article
ISSN
0950-9232

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## Abstract The epidermal growth factor (EGF) and __erb__B‐2 receptors are structurally related membrane‐bound tyrosine kinases. While these proteins exhibit close sequence homology, 50% overall and 80% in the tyrosine kinase domains, they respond very differently to heat stress. In NIH‐3T3 or NR6