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MAPK inhibition by 1α,25(OH)2–Vitamin D3 in breast cancer cells.: Evidence on the participation of the VDR and Src

✍ Scribed by Ana M Rossi; Daniela A Capiati; Gabriela Picotto; Silvia Benassati; Ricardo L Boland


Book ID
116697334
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
131 KB
Volume
89-90
Category
Article
ISSN
0960-0760

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## Abstract 1α,25‐Dihydroxyvitamin D~3~ [1α,25(OH)~2~D~3~], the hormonally active form of vitamin D~3~, has been shown to be a potent negative growth regulator of breast cancer cells both in vitro and in vivo. 1α,25(OH)~2~D~3~ acts through two different mechanisms. In addition to regulating gene tr