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MAP Kinase-Independent Induction of Proto-oncogene c-fos mRNA by Hemin in Human Cells

โœ Scribed by Yoshiro Masuya; Isamu Kameshita; Hitoshi Fujisawa; Hirao Kohno; Koshiro Hioki; Rikio Tokunaga; Shigeru Taketani


Book ID
115583943
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
186 KB
Volume
260
Category
Article
ISSN
0006-291X

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โœ Jan Skouv; Britta Christensen; Herman Autrup ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 633 KB

The effect of the skin tumor-promoter TPA (12-0-tetradecanoylphorbol-13-acetate) on expression of cellular proto-oncogenes has been examined in cell lines derived from human urothelium. A single treatment with TPA (1 pg/ml) increased the transcription of clfos and c-myc proto-oncogenes at least 20-f