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MAP kinase-dependent induction of clock gene expression by α1-adrenergic receptor activation

✍ Scribed by Masashi Akiyama; Yoichi Minami; Kouji Kuriyama; Shigenobu Shibata


Book ID
117105335
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
251 KB
Volume
542
Category
Article
ISSN
0014-5793

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## Abstract Many G protein coupled receptors (GPCRs) cause phosphorylation of MAP kinases through transactivation of the epidermal growth factor receptor (EGF‐R), leading to increased cell survival and growth, motility, and migration. Phosphoinositide 3‐kinase (PI3K) is one of the important cell su