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Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

✍ Scribed by Moro, L.


Book ID
111745751
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
424 KB
Volume
17
Category
Article
ISSN
0261-4189

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## Abstract Many G protein coupled receptors (GPCRs) cause phosphorylation of MAP kinases through transactivation of the epidermal growth factor receptor (EGF‐R), leading to increased cell survival and growth, motility, and migration. Phosphoinositide 3‐kinase (PI3K) is one of the important cell su