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Mannan-coated gelatin nanoparticles for sustained and targeted delivery of didanosine: In vitro and in vivo evaluation

✍ Scribed by Kaur, Amandeep; Jain, Subheet; Tiwary, Ashok K.


Book ID
115470455
Publisher
Versita
Year
2008
Tongue
English
Weight
170 KB
Volume
58
Category
Article
ISSN
1330-0075

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The release rate of 5-fluorouracil (5-FU) from lipid-coated nanoparticles (LNPs) was determined to develop a respirable delivery system for use as adjuvant (postsurgery) therapy for lung cancer. LNPs were prepared by spray drying, and the in vitro release was measured by microdialysis. The compositi