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In vitro and in vivo evaluation of a matrix-in-cylinder system for sustained drug delivery

✍ Scribed by E Mehuys; C Vervaet; I Gielen; H Van Bree; J.P Remon


Book ID
113690522
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
284 KB
Volume
96
Category
Article
ISSN
0168-3659

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The aim of this study was to estimate colon-specific drug delivery of a novel capsule (CS capsule). Theophylline was used as model drug and little was released from the CS capsules in the release medium mimicking physiological environment of stomach to small intestine. However, 66.7 +/- 8.8% theophy