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Manipulation of the Anabolic and Catabolic Responses With OP-1 and Zoledronic Acid in a Rat Critical Defect Model

โœ Scribed by David G Little; Michelle McDonald; Rick Bransford; Craig B Godfrey; Negin Amanat


Book ID
111485325
Publisher
American Society for Bone and Mineral Research
Year
2005
Tongue
English
Weight
572 KB
Volume
20
Category
Article
ISSN
0884-0431

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Manipulating the anabolic and catabolic
โœ Anna Kajsa Harding; Per Aspenberg; Masashi Kataoka; David Bylski; Magnus Tรคgil ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 198 KB

## Abstract Remodeling of a bone graft can be influenced both by anabolic substances, such as a bone morphogenic protein (BMP) and by anticatabolic substances, such as the bisphosphonates. BMPs are potent bone anabolic substances, but also boost catabolism and cause resorption. Bisphosphonates inhi