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Manipulation of the anabolic and catabolic responses with BMP-2 and zoledronic acid in a rat femoral fracture model

✍ Scribed by Yuji Doi; Masashi Miyazaki; Toyomi Yoshiiwa; Katsutoshi Hara; Masashi Kataoka; Hiroshi Tsumura

Book ID
116324944
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
886 KB
Volume
49
Category
Article
ISSN
8756-3282

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Manipulating the anabolic and catabolic
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## Abstract Remodeling of a bone graft can be influenced both by anabolic substances, such as a bone morphogenic protein (BMP) and by anticatabolic substances, such as the bisphosphonates. BMPs are potent bone anabolic substances, but also boost catabolism and cause resorption. Bisphosphonates inhi