Management of refractory essential thrombocythemia with anagrelide in a patient undergoing hemodialysis
✍ Scribed by Maria do Carmo Filomena Mesquita; Eugénie Bakoto Sol; Marianne Malarme; Denis Noubouossie; Anne Claire Demulder
- Book ID
- 113544080
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 113 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0149-2918
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📜 SIMILAR VOLUMES
The patient to be discussed today is an 8 1 ⁄2-year-old girl. She was referred to us in February 1994 when 4 years old because of recurrent severe headaches, paraesthesias of the extremities, erythromelalgia, abdominal pain, and a platelet count of between 1,300 and 1,500 × 10 9 /L. Physical examina
Plasmatic levels of PDGF-AB, TGFb 1 , and bFGF are increased in patients with essential thrombocythemia (ET) while intraplatelet levels are low for PDGF, normal for TGFb, and elevated for bFGF. To evaluate the contribution of gene expression to the dysregulated cytokine levels, we studied platelet P