Thiamine deficiency results in downregul
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Alan S. Hazell; Pierre Pannunzio; K.V. Rama Rao; David V. Pow; Andrea Rambaldi
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Article
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2003
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John Wiley and Sons
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English
β 368 KB
## Abstract Pyrithiamineβinduced thiamine deficiency (TD) is a wellβestablished model of Wernicke's encephalopathy in which a glutamateβmediated excitotoxic mechanism may play an important role in determining selective vulnerability. In order to examine this possibility, cultured astrocytes were ex