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Mammalian mismatch repair: error-free or error-prone?

✍ Scribed by Javier Peña-Diaz; Josef Jiricny


Book ID
113931674
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
391 KB
Volume
37
Category
Article
ISSN
0968-0004

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There is growing evidence that recombination is mutagenic and that some forms of DNA repair synthesis are error prone. DNA synthesis in mismatch repair might also be error prone. DNA-repair systems detect structural defects in DNA with high efficiency but they occasionally also strike at normal sect