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Mismatch-mediated error prone repair at the immunoglobulin genes

โœ Scribed by Richard Chahwan; Winfried Edelmann; Matthew D. Scharff; Sergio Roa

Book ID
116314414
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
305 KB
Volume
65
Category
Article
ISSN
0753-3322

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## Communicated by David Cooper Mutations of the PMS2 DNA repair gene predispose to a characteristic range of malignancies, with either childhood onset (when both alleles are mutated) or a partially penetrant adult onset (if heterozygous). These mutations have been difficult to detect, due to inte