Mammalian cell transformation and cell-mediated mutagenesis by carcinogenic polycyclic hydrocarbons
โ Scribed by Eliezer Huberman
- Book ID
- 113190639
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 384 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0027-5107
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Chemically nonโreactive carcinogens, such as polycyclic hydrocarbons, have to be metabolized by cellular enzymes in order to exert their biological effects including mutagenicity. Chinese hamster V79 cells can be efficiently mutated from 8โazaguanine susceptibility to resistance by Nโme
## Abstract Three potycyclic hydrocarbons, benz(__a__)anthracene, 3โmethylcholanthrene and 7,12โdimethylโbenz(__a__)anthracene, have been studied in a cellโmediated mutagenesis system using BHK 21 cells to metabolize the hydrocarbons and Vโ79 cells as targets for detecting induced cytotoxicity and