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Cell-mediated mutagenesis in cultured Chinese hamster cells by carcinogenic polycyclic hydrocarbons: Nature and extent of the associated hydrocarbon-DNA reaction

✍ Scribed by R.F. Newbold; C.B. Wigley; M.H. Thompson; P. Brookes

Book ID
113191148
Publisher
Elsevier Science
Year
1977
Tongue
English
Weight
984 KB
Volume
43
Category
Article
ISSN
0027-5107

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Cell-mediated mutagenesis in cultured ch
Cell-mediated mutagenesis in cultured chinese hamster cells by polycyclic hydrocarbons: Mutagenicity and DNA reaction related to carcinogenicity in a series of compounds
✍ Caroline B. Wigley; Robert F. Newbold; Jacqueline Amos; Peter Brookes 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 French ⚖ 598 KB

## Abstract Three potycyclic hydrocarbons, benz(__a__)anthracene, 3‐methylcholanthrene and 7,12‐dimethyl‐benz(__a__)anthracene, have been studied in a cell‐mediated mutagenesis system using BHK 21 cells to metabolize the hydrocarbons and V‐79 cells as targets for detecting induced cytotoxicity and