✦ LIBER ✦

Mammalian cell culture processes

✍ Scribed by Wei-Shou Hu; James M. Piret

Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 536 KB
Volume: 3
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(92)90137-8

No coin nor oath required. For personal study only.

✦ Synopsis

Over the past year, mammalian cell culture research has been aimed at investigating the influence of culture conditions on viability, productivity and the consistency of post-translational modifications. Studies of the effect of medium conditions and the development of kinetic models are being made in relation to current efforts to develop fed-batch strategies that will optimize recombinant protein production processes. Recent advances have included novel biosensor and bioreactor developments. New technologies have also been applied to investigate high cell density bioreactor and culture conditions.

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