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Malotilate, a Hepatoprotectant, Suppresses CYP2E1 Expression in Rats

✍ Scribed by S.G. Kim; J.Y. Kwak; J.W. Lee; R.F. Novak; S.S. Park; N.D. Kim

Book ID
115574640
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
407 KB
Volume
200
Category
Article
ISSN
0006-291X

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi