Malonyl coenzyme A and adiposity in the dahl salt-sensitive rat: Effects of pioglitazone
β Scribed by T.G. Kurowski; A.K. Saha; B.A. Cunningham; R.I. Holbert; J.R. Colca; B.E. Corkey; N.B. Ruderman
- Book ID
- 117180159
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 784 KB
- Volume
- 45
- Category
- Article
- ISSN
- 1532-8600
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When an βΌ30 centiMorgan (cM) region of chromosome 13 containing the renin gene from the Dahl saltβresistant rat (R) was introgressed into the Dahl saltβsensitive rat (S), the resulting congenic rat (designated S.R__βRen__) had a systolic blood pressure on a 2% (w/w) salt diet that was 24 mmHg lower
The cardiac atria are known to play a role in blood volume homeostasis, secreting a peptide that induces a potent natriuresis and diuresis. This peptide is atrial natriuretic factor (ANF), and its primary site of storage is within atria-specific granules found in atrial cardiocytes. Since salt load