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Malignant transformation of rat embryo fibroblasts by herpes simplex virus types 1 and 2 at suboptimal temperature

✍ Scribed by DARAI, GHOLAMREZA; BRAUN, RÜDIGER; FLÜGEL, ROLF MANFRED; MUNK, KLAUS


Book ID
109703957
Publisher
Nature Publishing Group
Year
1977
Tongue
English
Weight
398 KB
Volume
265
Category
Article
ISSN
0028-0836

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## Abstract Six oncogenically transformed cell lines were obtained following infection of hamster embryo fibroblasts with UV‐irradiated herpes simplex virus type 2 (HSV‐2) or with an HSV‐2 temperature‐sensitive mutant. All lines produced undifferentiated fibrosarcomas in newborn hamsters, four of t