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Malignant melanoma and renal cell carcinoma: Immunological and haematological effects of recombinant human interleukin-2

✍ Scribed by Khizar Hayat; Sheila Rodgers; Lesley Bruce; Robert C. Rees; Karen Chapman; Steve Reeder; Mark S. Dorreen; Eamonn Sheridan; Thiagarajan Sreenivasan; Barry W. Hancock


Book ID
119156992
Publisher
Elsevier Science
Year
1991
Weight
809 KB
Volume
27
Category
Article
ISSN
0277-5379

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A phase I study of recombinant human int
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Preclinical data suggest synergy of interleukin-2 (IL-2) combined with alphainterferon (IFN). In addition, toxicities of IL-2 may be decreased by intermittent continuous infusion. The purpose of this trial was to determine the maximum tolerated dose (MTD) of recombinant IL-2 combined with alpha-IFN