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Malignant germ cell tumours in two siblings

✍ Scribed by Blake, Kathryn I. ;Gerrard, Mary P.

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
190 KB
Volume
21
Category
Article
ISSN
0098-1532

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✦ Synopsis

Abstract

Familial germ cell tumours are well recognised in kinship with gonadal dysgenesis, but their occurrence in siblings with normal chromosomes is rare. We report two sisters who presented within a 4 month period with malignant ovarian germ cell tumours; one a dysgerminoma and the other a mixed tumour with marked choriocarcinomatous elements. Both children had a normal female constitutional karyotype and normal phenotype. Β© 1993 Wiley‐Liss, Inc.

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