## Background: Brain metastases of pediatric germ cell tumors are uncommon, and there is limited information regarding their incidence, clinical presentation, response to treatment, and influence on survival. ## Methods: The authors reviewed the experience with brain metastases from pediatric ger
Malignant germ cell tumors in 57 children and adolescents
โ Scribed by Garrett M. Brodeur; Cathryn B. Howarth; Charles B. Pratt; Josefina Caces; H. Omar Hustu
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 760 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0008-543X
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The outlook for patients with germ cell tumors was poor before the advent of effective chemotherapy. In this study the outcome of multiagent chemotherapy in children treated for germ cell tumor is assessed. Between January 1984 and December 1990, 107 patients were diagnosed to have germ cell tumors.
The present paper is a retrospective study of one hundred and thirty five germ cell tumors seen in children at the University Hospital, Varanasi during a period of 21 years. These tumors constituted 7.5% of all solid tumors in the pediatric age group. Histologically 89 tumors (65.9%) were benign and