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Malignant and transforming activity of rous sarcoma virus. II. The study of variants of rous sarcoma virus isolated from mouse tumours

✍ Scribed by I. B. Obukh; I. N. Kryukova

Publisher
John Wiley and Sons
Year
1969
Tongue
French
Weight
263 KB
Volume
4
Category
Article
ISSN
0020-7136

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✦ Synopsis

Virus variants from Af mouse tumours induced by syngeneic cultured cells infected with Carr-Zilber strain of Rous sarcoma virus were studied. These variants were highly oncogenic for adult mice and golden hamsters thus differing from the original Carr-Zilber strain. The coat antigens of these viruses were not different from those of the original strain. By means of fusion with normal chicken jibroblasts an R S V variant was isolated from transformed non-malignant cultures. This virus did not differ, in its oncogenicity for adult hamsters and mice, from variants isolated from mouse turnours.

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