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Maleic acid-induced impaired conversion of 25(OH)D3 to 1,25(OH)2D3: Implications for Fanconi's syndrome

โœ Scribed by Brewer, Eileen D; Tsai, Huan C; Szeto, King-Seing; Morris, R Curtis


Book ID
109877142
Publisher
Nature Publishing Group
Year
1977
Tongue
English
Weight
778 KB
Volume
12
Category
Article
ISSN
0085-2538

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1,25-dihydroxy-vitamin D(3) (1,25(OH)(2)D(3)), the hormonally active form of vitamin D(3), acts through two different mechanisms. In addition to regulating gene expression via the specific intracellular vitamin D receptor (VDR), 1,25(OH)(2)D(3) induces rapid, non-transcriptional responses involving