Male X-linked genes inDrosophila melanogasterare compensated independently of the Male-Specific Lethal complex
β Scribed by Philip, Philge; Stenberg, Per
- Book ID
- 121608509
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 336 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1756-8935
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## Abstract The uses of experimental chimeras to transmit lethal genes are discussed. As an example, the Xβlinked lethal mutation __jp__ was genetically transmitted by a chimeric male. This male produced abnormal offspring when bred to __jpl__ + and __msd/__ + females. Thus, allelism of the mutatio
## Abstract The upregulation of the JILβ1 kinase on the male X chromosome and its association with the maleβspecific lethal (MSL) complex suggest that JILβ1 may play a role in regulating dosage compensation. To directly test this hypothesis we measured eye pigment levels of mutants in the Xβlinked