✦ LIBER ✦
Use of chimeras to transmit lethal genes in the mouse and to demonstrate allelism of the two X-linked male lethal genesjp andmsd
✍ Scribed by Eicher, Eva M. ;Hoppe, Peter C.
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 350 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0022-104X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The uses of experimental chimeras to transmit lethal genes are discussed. As an example, the X‐linked lethal mutation jp was genetically transmitted by a chimeric male. This male produced abnormal offspring when bred to jpl + and msd/ + females. Thus, allelism of the mutations jp and msd is proven and the symbol for msd should be changed to jp^msd^.