𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Major role of the soluble interleukin-6/interleukin-6 receptor complex for the proliferation of interleukin-6-dependent human myeloma cell lines

✍ Scribed by Jean-Philippe Gaillard; Janny Liautard; Bernard Klein; Jean Brochier


Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
695 KB
Volume
27
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


The prognostic value of soluble interleu
✍ Roberto Stasi; Maurizio Brunetti; Albertina Parma; Claudio Di Giulio; Edmondo Te πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 122 KB πŸ‘ 2 views

## Background: The effect of interleukin-6 (il-6), the major growth factor for myeloma cells, may be enhanced by soluble il-6 receptor (sil-6r). therefore, the current study investigated the clinical significance of serum sil-6r in patients with multiple myeloma (mm). ## Methods: Serum levels of

Expression of the murine interleukin 6 r
✍ Maria Teresa Fiorillo; Carlo Toniatti; Jacques Van Snick; Gennaro Ciliberto πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 604 KB

This paper reports on cDNA coding for the SO-kDa murine IL6 receptor (mlL6R) that was cloned from a mouse liver cDNA library. Human hepatoma Hep3B cells transfected transiently or stably with an expression vector carrying the entire coding region for mIL6R become responsive to mouse IL6 (mIL 6).We m

A NOVEL AND RAPID PREDICTION ASSAY FOR T
✍ Valeria Lia Varga; Andras Falus; Eva Pallinger; IstvΓ‘n NovΓ‘k; KristΓ³f A. FΓΌlΓΆp; πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 123 KB

Interleukin-6 (IL-6) belongs to a family of cytokines that use receptors consisting of a common signal-transducing chain (gp130). Baf/3 cells transfected with the human IL-6 receptor (IL-6R) and gp130 (Baf/3-gp130/IL-6R) can only grow in medium containing IL-6. We attempted to interrupt the signal t

Tocilizumab, a humanized anti-interleuki
✍ Toshio Tanaka; Keisuke Hagihara; Yoshihito Shima; Masashi Narazaki; Atsushi Ogat πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 197 KB

## Abstract The cytokine interleukin (IL)‐6 has a wide range of biological activities. It contributes to host defense against pathogens by inducing immune responses, hematopoiesis, and acute‐phase reactions. However, dysregulation of IL‐6 production plays a significant pathological role in various

Lipoxygenase metabolism is required for
✍ Alan M. Miller; Beverly Steele Allen; Vincent Ziboh πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 184 KB

The cell line M-07e requires either Interleukin-3 (IL-3) or granulocyte-macrophage colony stimulating factor (GM-CSF) for proliferation in vitro. Cells deprived of growth factor for up to 48 hours remain viable but no longer divide. The growthfactor-deprived M-07e cells begin to divide within 48 hou

Interleukin-6 induces tyrosine phosphory
✍ Carola Neumann; Gundula Zehentmaier; Susanne Danhauser-Riedl; Bertold Emmerich; πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 701 KB

## Interleukin-6 induces tyrosine phosphorylation of the Ras activating protein Shc, and its complex formation with Grb2 in the human multiple myeloma cell line LP-1 Like many other cytokines and growth factors, interleukin-6 (IL-6) activates ~21'"'. However, the precise biochemical mechanisms ind