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Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3

✍ Scribed by Williams, Luke M; Rudensky, Alexander Y

Book ID
109923341
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
612 KB
Volume
8
Category
Article
ISSN
1529-2908

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## Abstract Current literature suggests that T cells recognizing antigen on mature dendritic cells (DC) differentiate into effector T cells whereas tolerance is induced when antigen is presented by immature DC. We investigated the consequences of the interactions between immature or lipopolysacchar