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Magnetically manipulable polymeric supports for solid phase organic synthesis

โœ Scribed by Michael J. Szymonifka; Kevin T. Chapman

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
258 KB
Volume
36
Category
Article
ISSN
0040-4039

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The nature of the polymer support plays an integral role in solid phase organic synthesis. Combinatorial and highly parallel synthetic strategies have stimulated the development of new polymer support materials with compositions and properties that allow a broader spectrum of organic transformations

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The solid-phase synthesis of small organic molecules has received renewed attention since the first reports of the polymer-supported synthesis of compounds of therapeutic interest. Solid-phase synthesis is now a key component of the high-throughput synthesis and screening approach to drug discovery.