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Magnetic Resonance Imaging Traits in Siblings Discordant for Alzheimer Disease

✍ Scribed by Karen T. Cuenco; Robert C. Green; J. Zhang; Kathryn Lunetta; Porat M. Erlich; L. Adrienne Cupples; Lindsay A. Farrer; Charles DeCarli; for the MIRAGE Study Group

Book ID
109268198
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
143 KB
Volume
18
Category
Article
ISSN
1051-2284

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## Abstract We performed three‐dimensional, high‐resolution magnetic resonance imaging (MRI) of fixed mouse brains to determine whether MRI can detect amyloid plaques in transgenic mouse models of Alzheimer's disease. Plaque‐like structures in the cortex and hippocampus could be clearly identified