Magnesium deficiency up-regulates Myod expression in rat skeletal muscle and C2C12 myogenic cells

Dual-regulated myoD- and msx1-based inte

Dual-regulated myoD- and msx1-based interventions in C2C12-derived cells enable precise myogenic/osteogenic/adipogenic lineage control

✍ Cornelia Fux; Dominik Langer; Martin Fussenegger 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 463 KB

## Abstract ## Background Advanced gene therapy, tissue engineering and biopharmaceutical manufacturing require sophisticated and well‐balanced multiregulated multigene interventions to reprogram desired mammalian cell phenotypes. ## Methods We have combined the streptogramin (PIP)‐ and tetracyc