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MAdCAM-1 expression in human intestinal microvascular endothelial cells (HIMEC) is regulated by the PI3K/Akt and NFkB pathways

โœ Scribed by Hitoshi Ogawa; Parvaneh Rafiee; Pamela Fisher; Nathan Johnson; Jan Heidemann; Mary Otterson; David G. Binion


Book ID
119427590
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
177 KB
Volume
124
Category
Article
ISSN
0016-5085

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## Abstract Both leptin and vascular endothelial growth factor (VEGF) are growth and angiogenic cytokines that are upregulated in different types of cancer and have been implicated in neoplastic progression. Here we investigated the molecular mechanism by which leptin and VEGF expression are regula