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Icariin stimulates angiogenesis by activating the MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways in human endothelial cells

✍ Scribed by Byung-Hee Chung; Jong-Dai Kim; Chun-Ki Kim; Jung Huan Kim; Moo-Ho Won; Han-Soo Lee; Mi-Sook Dong; Kwon-Soo Ha; Young-Geun Kwon; Young-Myeong Kim

Book ID
116297407
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
234 KB
Volume
376
Category
Article
ISSN
0006-291X

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In vitro experiments have shown that the establishment of cell-cell contacts in intestinal epithelial cell cultures is a critical step in initiating ERK inhibition, cell cycle arrest, and induction of the differentiation process. Herein, we determined the mechanisms through which E-cadherin-mediated