Facioscapulohumeral muscular dystrophy (FSHD), caused by partial deletion of the D4Z4 macrosatellite repeat on chromosome 4q, has a complex genetic and epigenetic etiology. To develop FSHD, D4Z4 contraction needs to occur on a specific genetic background. Only contractions associated with the 4qA161
Macrosatellite epigenetics: the two faces of DXZ4 and D4Z4
β Scribed by Brian P. Chadwick
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 227 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0009-5915
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