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Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin

✍ Scribed by Otero, Karel; Turnbull, Isaiah R; Poliani, Pietro Luigi; Vermi, William; Cerutti, Elisa; Aoshi, Taiki; Tassi, Ilaria; Takai, Toshiyuki; Stanley, Samuel L; Miller, Mark


Book ID
109920792
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
678 KB
Volume
10
Category
Article
ISSN
1529-2908

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## Abstract Mouse bone marrow‐derived macrophages proliferate in the presence of macrophage colony‐stimulating factor (M‐CSF), granulocyte‐macrophage colony‐stimulating factor, or IL‐3, but undergo apoptosis in their absence. Inhibition of extracellular signal‐regulated kinases (ERK)‐1/2 blocks gro