Both tumor necrosis factor-a and interferon-y are involved in the activation of macrophage cytocidal/cytostatic effector function. Recent studies provide evidence that, in non-septic inflammatory disease, T cells may activate macrophages primed by interferon-y either by providing tumor necrosis fact
Macrophage activation by T cells
โ Scribed by Donna M. Paulnock
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 883 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
โฆ Synopsis
In the past year, the application of biochemical and molecular approaches to the analysis of macrophage activation by T cells has provided new information concerning the regulation of gene expression during the activation process, and advanced our understanding of the multiple mechanisms that influence the development of macrophage function during an immune response.
๐ SIMILAR VOLUMES
## Macrophage activation by interferon-y from host-protective T cells is inhibited by interleukin (IL) 3 and IL4 produced by disease-promoting T cells in leishmaniasis BALBlc mice are highly susceptible to Leishmania major infection. They develop a progressive fatal disseminating disease even with