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Macromolecular crowding effects on protein–protein binding affinity and specificity

✍ Scribed by Kim, Young C.; Best, Robert B.; Mittal, Jeetain

Book ID
121273638
Publisher
American Institute of Physics
Year
2010
Tongue
English
Weight
682 KB
Volume
133
Category
Article
ISSN
0021-9606

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## Abstract In cells, proteins execute specific tasks in crowded environments; these environments influence their stability and dynamics. Similarly, for an enzyme molecule encapsulated in an inorganic cavity as in biosensors or biocatalysts, confinement or excluded volume plays an important role in