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Macromolecular Co-Conjugates of Methotrexate and Ferrocene in the Chemotherapy of Cancer

✍ Scribed by Alain I. Mufula; B. A. Aderibigbe; Eberhard W. Neuse; Hembe E. Mukaya

Book ID
113071415
Publisher
Springer
Year
2011
Tongue
English
Weight
299 KB
Volume
22
Category
Article
ISSN
1053-0495

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Antineoplastic drugs such as daunomycin, adriamycin, methotrexate, 5-fluorouridine, cytosine arabinoside, and platinate were bound to antibodies directly or via a polymeric bridge. The drug antibody conjugates retained most oftheir drug and antibody activities when tested in oitro. Daunomycin-antibo