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Maclafungin, a new antifungal macrocyclic lactone from Actinomycete sp. Y-8521050

✍ Scribed by Triptikumar Mukhopadhyay; S.R. Nadkarni; M.V. Patel; R.G. Bhat; K.R. Desikan; B.N. Ganguli; R.H. Rupp; H.-W. Fehlhaber; H. Kogler

Book ID: 104208892
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 354 KB
Volume: 54
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(98)00838-2

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✦ Synopsis

A new antifungal macrocyclic lactone maclafungin, belonging to the oligomycin class has been isolated from an actinomycete sp. Y-8521050. The antibiotic, having a molecular formula of C46H80012 , is active against several fungal species. Its structure was elucidated by analysis of 2D NMR experiments.

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