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M2065 Crohn's Associated Genes ATG16L1 and IRGM Are Not Associated with Granuloma Formation

✍ Scribed by Wolfkamp, Simone C.; Stokkers, Pieter C.; Te Velde, Anje A.


Book ID
122805397
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
90 KB
Volume
134
Category
Article
ISSN
0016-5085

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Autophagy gene ATG16L1 but not IRGM is a
✍ Devendra K. Amre; David R. Mack; Kenneth Morgan; Alfreda Krupoves; Irina Costea; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 94 KB πŸ‘ 2 views

Background: Recent genome-wide studies have implicated the autophagy genes ATG16L1 and IRGM in the pathogenesis of Crohn's disease (CD). We investigated whether these genes were associated with CD in Canadian children. ## Methods: A case-control study was carried out at 2 pediatric gastroenterolog