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97 Detailed Analysis of ATG16L1 Demonstrates Gene-Wide Extent of Association With Crohn's Disease Susceptibility

✍ Scribed by Johan Van Limbergen; Boyko Kabakchiev; Joanne M. Stempak; L. Philip Schumm; Wei Xu; Paul Henderson; Niddk IBD Genetics Consortium; Anne M. Griffiths; Stephen Girardin; Dana Philpott; Mark S. Silverberg

Book ID
119432937
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
90 KB
Volume
142
Category
Article
ISSN
0016-5085

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Confirmation of the role of ATG16l1 as a
Confirmation of the role of ATG16l1 as a Crohn's disease susceptibility gene
✍ J.R. Fraser Cummings; Rachel Cooney; Saad Pathan; Carl A. Anderson; Jeffrey C. B πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 93 KB

Background: A German genome-wide nonsynonymous single nucleotide polymorphism (nsSNP) association study identified ATG16L1 as a Crohn's disease (CD) susceptibility gene. The association appeared to be confined to the nsSNP rs2241880 and was confirmed in 2 German independent case-control collections