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Evidence of expression variation and allelic imbalance in Crohn's disease susceptibility genes NOD2 and ATG16L1 in human dendritic cells

✍ Scribed by Hu, Jianzhong; Peter, Inga


Book ID
123313747
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
662 KB
Volume
527
Category
Article
ISSN
0378-1119

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Background: IBD5, IL23R, and ATG16L1 genetic variations are established Crohn's disease (CD) risks alleles. We evaluated these in a population-based case-control study within a cohort to determine their penetrance, population attributable risk, independence, and relationship to other established CD