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M1809 Natural Killer Cells Target HCV Core Protein in Naïve Immune Response in HCV Transgenic Mice

✍ Scribed by Kenichi, Satoh; Hiroki, Takahashi; Michinori, Kohara; Toshifumi, Ohkusa; Mikio, Zeniya; Hisao, Tajiri


Book ID
122768597
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
135 KB
Volume
136
Category
Article
ISSN
0016-5085

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Natural killer cells target HCV core pro
✍ Kenichi Satoh; Hiroki Takahashi; Chiho Matsuda; Toshiyuki Tanaka; Masayuki Miyas 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 307 KB

## Abstract The mechanism of the innate immune response to hepatitis C virus (HCV) has not been fully elucidated, largely due to the lack of an appropriate model. We used HCV transgenic (Tg) mice, which express core, E1, E2, and NS2 proteins regulated by the Cre/__loxP__ switching expression system