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HCV core protein modulates the immune response against the HBV surface antigen in mice

✍ Scribed by Julio C Aguilar; Nelson Acosta-Rivero; Santiago Dueñas-Carrera; Juan Morales Grillo; Dagmara Pichardo; Dioslaida Urquiza; Gerardo Guillen; Verena Muzio

Book ID
116287035
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
112 KB
Volume
310
Category
Article
ISSN
0006-291X

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## Abstract The mechanism of the innate immune response to hepatitis C virus (HCV) has not been fully elucidated, largely due to the lack of an appropriate model. We used HCV transgenic (Tg) mice, which express core, E1, E2, and NS2 proteins regulated by the Cre/__loxP__ switching expression system