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Lymphotoxin-β receptor mediates NEMO-independent NF-κB activation

✍ Scribed by Tatsuya Saitoh; Hiroyasu Nakano; Naoki Yamamoto; Shoji Yamaoka


Book ID
117104869
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
267 KB
Volume
532
Category
Article
ISSN
0014-5793

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## Abstract Lymphotoxin beta receptor (LTβR) activation on mouse fibrosarcoma cells (BFS‐1) results in enhanced solid tumor growth paralleled by increased angiogenesis induced by the expression of pro‐angiogenic CXCL2. In our study, we demonstrate that both functional ligands of the LTβR, namely LT